Getting Your Sugar Fix: A Guide to Glycan Microarrays

Dr. Richard D. Cummings, faculty member in BCDB and IMP, is featured in an article in The Scientist for his glycobiology research including glycans and microarrays. 

Glycan microarrays consist of small quantities of a variety of natural or synthetic oligosaccharides affixed to a surface. Researchers use the arrays to identify proteins, cells, and microbes that bind to the sugars. Because printed microarrays require minuscule quantities of sugars, they made it possible, for the first time, to broadly screen proteins’ glycan affinities.

And while DNA microarrays’ glory days may be fading as RNA sequencing prices fall, the future of glycan microarrays appears sunny. “I think that [glycan microarrays are] really just about to, in the next five years, come into their own in terms of commercial use, industrial applications, and clinical use,” says Cummings.

Click here to read the full article in The Scientist.