What are rods and rings?

This image of mouse embryonic fibroblasts comes from Cara Schiavon, a Cancer Biology graduate student in Rick Kahn’s lab in the Department of Biochemistry. Dr. Kahn is a faculty member in the BCDB and CB programs.

The light green shapes are “Rods and Rings,” structures that were identified just a few years ago by scientists studying how cells respond to antiviral drugs, such as those used against hepatitis C.

The rod and ring structures appear to contain enzymes that cells use for synthesizing DNA building blocks. Patients treated with some antiviral drugs develop antibodies against these enzymes.

Click here to view the full story in Lab Land - The Health Sciences Research Blog.