Core Facilities

Emory University School of Medicine Service Center Facilities

A number of shared Core Facilities have been developed in the School of Medicine, which are available to all University researchers and students. More details can be found at the School of Medicine website, and a few core facilities have been highlighted below.

Yerkes Imaging Center

One of the major developments in neuroscience research at Emory is the opening of a new state-of-the-art brain imaging Core Facility in the neuroscience research building at the Yerkes Primate Center. This facility houses two magnetic-resonance-imaging (MRI) labs (a 7T/40cm Bruker system and a 3T/90cm human-size scanner Siemens system), a microPET lab, an optical/speckle imaging lab, a cyclotron, large radiochemistry lab, as well as wet lab and animal prep rooms. These resources, accessible to all faculty members of Emory University, are dedicated to research and education. This outstanding facility represents a keystone for the development and growth of faculty research programs focused towards various aspects of behavioral and cognitive neurosciences as well as translational research in neurological and psychiatric diseases. Dr. Leonard Howell, a well established and internationally renowned neuroscience training faculty member, is the director of the Yerkes brain imaging centers.

Biomedical Imaging Technology Center

This core facility, directed by Dr. Xiaoping Hu (Training Faculty NS Program), provides the organization and infrastructure for two operational units: The Emory Positron Emission Tomography (PET) Unit and the Magnetic Resonance Imaging (MRI) Research Unit. The PET Unit, located in the Emory University Hospital (immediately adjacent to the Department of Neurology and Psychiatry laboratories), houses two high resolution PET scanners, a cyclotron and laboratories for radioligand development and image analysis. Some MRIs are also located in the Emory University Hospital, but additional equipment is also installed in the new Psychology and Interdisciplinary Science building and at the Wesley Wood Geriatric Center. This equipment is mainly used for human studies. There are at least 15 PhD students in the graduate Neuroscience Program who actively use these MRI and PET imaging facilities for their thesis project.

Robert P. Apkarian Integrated Electron Microscopy Core

The Integrated Electron Microscopy Core is directed by Dr. Elizabeth Wright, Assistant Professor in the Department of Pediatrics. It provides expertise, service and training in transmission EM and EM immunocytochemistry. There are also hands-on workshops that enable investigators to learn techniques, such as immunogold labeling of specimens.

Biomarkers Core Lab, Yerkes

The Biomarkers Core Lab, directed by Dr. Mark Wilson, provides immunoassay determinations of steroid and protein hormones or other biologically active compounds in biological fluids. The laboratory currently provides determinations of over sixty compounds validated for nonhuman primates and humans. Services are provided to all Emory scientists for research purposes.

Transgenic Mouse & Gene Targeting Core

The Transgenic Mouse and Gene Targeting Core Facility is a shared resource of the Emory University School of Medicine. The core acts to provide both state of the art equipment and expertise for the generation and characterization of genetically altered mouse models. The core provides a full range of services in three major categories: Trangenic Mouse Production, Gene-Targeted Mice, and Auxiliary Services (characterization, maintenance, and preservation of novel mouse models.

Core Facility for Flow Cytometry

The Emory University School of Medicine Core Facility for Flow Cytometry provides analysis and sorting services to the research community in and around the Emory University Campus. It also provides training and consultation services to investigators wishing to utilize the Core.

The Rodent Behavioral Core

The School of Medicine Rodent Behavioral Core provides planning, execution, and analysis of behavioral experiments examining activity, arousal, coordinated movement, learning and memory, anxiety, depression, seizure susceptibility, reward/reinforcement, and aggression in mice and rats. Additional tests can potentially be developed on a case-by-case basis. The Behavioral Core also offers several rodent surgical services and assistance in IACUC protocol preparation. Directed by Jason Schroeder, Ph.D. and David Weinshenker, Ph.D., the Core is located in the vivarium of the Whitehead Biomedical Research Building.

NINDS Core Facilities

These core facilities are mainly funded by the NINDS and jointly supported by the Emory School of Medicine. They comprise the following cores for use at reduced rates to all Emory NINDS-funded investigators:

  • Neuropathology and Histochemistry Core
  • Viral Vector Core
  • Microscopy Core
  • Genetics and Expression Core
  • Proteomics Core

This center is led by Dr. Allan Levey, chair of Neurology and faculty member of the Emory graduate Neuroscience Program.