Student Publications
2021
Congrats to BCDB student Courtney Matheny (Benian lab) for her co-first author paper published in Protein Science! Mutations in conserved residues of the myosin chaperone UNC-45 result in both reduced stability and chaperoning activity. Moncrief T, Matheny CJ, Gaziova I, Miller J, Qadota H, Benian GM, Oberhauser AF. Protein Sci. 2021; doi: 10.1002/pro.4180. PMID: 34515376.
Congrats to BCDB student Raven Peterson (Koval lab) for her first author review published in Front Cell Dev Bio! Above the Matrix: Functional Roles for Apically Localized Integrins. Peterson RJ, Koval M. Front Cell Dev Biol. 2021;9:699407. doi: 10.3389/fcell.2021.699407. PMID: 34485286.
Congrats to BCDB student Raven Peterson (Koval lab) for her second author paper published in Physiol Rep! Sphingomyelinase decreases transepithelial anion secretion in airway epithelial cells in part by inhibiting CFTR-mediated apical conductance. Cottrill KA, Peterson RJ, Lewallen CF, Koval M, Bridges RJ, McCarty NA. Physiol Rep. 2021;9(15):e14928. doi: 10.14814/phy2.14928. PMID: 34382377.
Congrats to BCDB student Emily Weikum (Ortlund lab) for her second author paper published in Nucleic Acids Res! Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element. Liu X, Weikum ER, Tilo D, Vinson C, Ortlund EA. Nucleic Acids Res. 2021;49(15):8923-33. doi: 10.1093/nar/gkab605. PMID: 34289059.
Congrats to BCDB student Elizabeth Minten (Yu lab) for her first author paper published in Cell Rep! SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation. Minten EV, Kapoor-Vazirani P, Li C, Zhang H, Balakrishnan K, Yu DS. Cell Rep. 2021 Mar 30;34(13):108921. doi: 10.1016/j.celrep.2021.108921. PMID: 33789098.
Congrats to BCDB student Isabela Suster (Feng lab) for her first author review published in Int J Mol Sci! Multifaceted Regulation of MicroRNA Biogenesis: Essential Roles and Functional Integration in Neuronal and Glial Development. Suster I, Feng Y. Int J Mol Sci. 2021; 23;22(13):6765. doi: 10.3390/ijms22136765. PMID: 34201807.
Congrats to BCDB student Maria Sterrett (Corbett lab) for her first author paper published in RNA! A budding yeast model for human disease mutations in the EXOSC2 cap subunit of the RNA exosome complex. Sterrett MC, Enyenihi L, Leung SW, Hess L, Strassler SE, Farchi D, Lee RS, Withers ES, Kremsky I, Baker RE, Basrai MA, van Hoof A, Fasken MB, Corbett AH. RNA. 2021;27(9):1046-1067. doi: 10.1261/rna.078618.120. PMID: 34162742.
Congrats to BCDB student Samantha Schwartz (Conn lab) for her middle author paper published in Science Immunology! Heterozygous OAS1 gain-of-function variants cause an autoinflammatory immunodeficiency. Magg T, Okano T, Koenig LM, Boehmer DFR, Schwartz SL, Inoue K, Heimall J, Licciardi F, Ley-Zaporozhan J, Ferdman RM, Caballero-Oteyza A, Park EN, Calderon BM, Dey D, Kanegane H, Cho K, Montin D, Reiter K, Griese M, Albert MH, Rohlfs M, Gray P, Walz C, Conn GL, Sullivan KE, Klein C, Morio T, Hauck F. Sci Immunol. 2021;6(60):eabf9564. doi: 10.1126/sciimmunol.abf9564. PMID: 34145065.
Congrats to BCDB student Sabrina Lynn (Koval lab) for her first author paper published in Tissue Barriers! Asymmetric distribution of dynamin-2 and β-catenin relative to tight junction spikes in alveolar epithelial cells. Lynn KS, Easley KF, Martinez FJ, Reed RC, Schlingmann B, Koval M. Tissue Barriers. 2021:1929786. doi: 10.1080/21688370.2021.1929786. PMID: 34107845.
Congrats to BCDB student Emily Legan (Li lab) for her middle author paper published in Nat Communications! Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module. Arce NA, Cao W, Brown AK, Legan ER, Wilson MS, Xu ER, Berndt MC, Emsley J, Zhang XF, Li R. Nat Commun. 2021;12(1):2360. doi: 10.1038/s41467-021-22634-x. PMID: 33883551.
Congrats to BCDB student Eric Hoffer (Dunham lab) for his middle author paper published in Nat Communications! trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo. Aron ZD, Mehrani A, Hoffer ED, Connolly KL, Srinivas P, Torhan MC, Alumasa JN, Cabrera M, Hosangadi D, Barbor JS, Cardinale SC, Kwasny SM, Morin LR, Butler MM, Opperman TJ, Bowlin TL, Jerse A, Stagg SM, Dunham CM, Keiler KC. Nat Commun. 2021;12(1):1799. doi: 10.1038/s41467-021-22012-7. PMID: 33741965.
Congrats to BCDB student Tyler Moser-Katz (Boise lab) for his first author review published in Front Oncology! Game of Bones: How Myeloma Manipulates Its Microenvironment. Moser-Katz T, Joseph NS, Dhodapkar MV, Lee KP, Boise LH. Front Oncol. 2021;10:625199. doi: 10.3389/fonc.2020.625199. eCollection 2020. PMID: 33634031
Congrats to BCDB student Rachel Turn (Kahn lab) for her first author paper published in Mol Biol Cell! Roles for ELMOD2 and Rootletin in ciliogenesis. Turn RE, Linnert J, Gigante ED, Wolfrum U, Caspary T, Kahn RA. Mol Biol Cell. 2021;32(8):800-822. doi: 10.1091/mbc.E20-10-0635. PMID: 33596093.
Congrats to BCDB student Maria Cilento (Sarafianos lab) for her first author review published in Chem Rev! Avoiding Drug Resistance in HIV Reverse Transcriptase. Cilento ME, Kirby KA, Sarafianos SG. Chem Rev. 2021;121(6):3271-3296. doi: 10.1021/acs.chemrev.0c00967. PMID: 33507067.
Congrats to BCDB student Lauren Jeffers (Koval lab) for her second author review published in Methods Mol Biol! Measurement of Lung Vessel and Epithelial Permeability In Vivo with Evans Blue. Smith P, Jeffers LA, Koval M. Methods Mol Biol. 2021;2367:137-148. doi: 10.1007/7651_2020_345. PMID: 33460025
2020
Congrats to BCDB student Emma D’Agostino (Ortlund lab) for her first middle paper published in Sci Reports! Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist. Mays SG, Stec J, Liu X, D'Agostino EH, Whitby RJ, Ortlund EA. Sci Rep. 2020;10(1):22279. doi: 10.1038/s41598-020-79251-9. PMID: 33335203.
Congrats to BCDB student Raven Shah (Sarafianos lab) for his first author review published in J of Vis Exp! Single-cell Multiplexed Fluorescence Imaging to Visualize Viral Nucleic Acids and Proteins and Monitor HIV, HTLV, HBV, HCV, Zika Virus, and Influenza Infection. Shah R, Lan S, Puray-Chavez MN, Liu D, Tedbury PR, Sarafianos SG. J Vis Exp. 2020;(164):10.3791/61843. doi: 10.3791/61843. PMID: 33191939.
Congrats to BCDB student Sean Kundinger (Seyfried lab) for his first author paper published in J Proteome Res! Middle-Down Proteomics Reveals Dense Sites of Methylation and Phosphorylation in Arginine-Rich RNA-Binding Proteins. Kundinger SR, Bishof I, Dammer EB, Duong DM, Seyfried NT.J Proteome Res. 2020;19(4):1574-1591. doi: 10.1021/acs.jproteome.9b00633. PMID: 31994892.
Congrats to BCDB student Eric Hoffer (Dunham lab) for his first author paper published in eLife! Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Hoffer ED, Hong S, Sunita S, Maehigashi T, Gonzalez RL Jnr, Whitford PC, Dunham CM. Elife. 2020;9:e51898. doi: 10.7554/eLife.51898. PMID: 33016876.
Congrats to BCDB student Sean Kundinger (Seyfried lab) for his second author paper published in Sci Datal! Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease. Ping L, Kundinger SR, Duong DM, Yin L, Gearing M, Lah JJ, Levey AI, Seyfried NT.Sci Data. 2020;7(1):315. doi: 10.1038/s41597-020-00650-8.PMID: 32985496.
Congrats to BCDB student Courtney (Christian) Matheny (Benian lab) for her first author paper published in Aging Cell! Animal models of sarcopenia. Christian CJ, Benian GM. Aging Cell. 2020;19(10):e13223. doi: 10.1111/acel.13223. PMID: 32857472.
Congrats to BCDB student Courtney (Christian) Matheny (Benian lab) for her middle author paper published in Biophys J! Mutational Analysis of the Structure and Function of the Chaperoning Domain of UNC-45B. Gaziova I, Moncrief T, Christian CJ, Villarreal M, Powell S, Lee H, Qadota H, White MA, Benian GM, Oberhauser AF. Biophys J. 2020;119(4):780-791. doi: 10.1016/j.bpj.2020.07.012. PMID: 32755562.
Congrats to BCDB student Ed Quach (Li lab) for his first author paper published in J ThrombHaemost! Structure-function of platelet glycoprotein Ib-IX. Quach ME, Li R. J Thromb Haemost. 2020;18(12):3131-3141. doi: 10.1111/jth.15035. PMID: 32735697.
Congrats to BCDB student Samantha Schwartz (Conn lab) for her first author paper published in Nucleic Acids Research! Human OAS1 activation is highly dependent on both RNA sequence and context of activating RNA motifs. Schwartz SL, Park EN, Vachon VK, Danzy S, Lowen AC, Conn GL. Nucleic Acids Res. 2020;48(13):7520-7531. doi: 10.1093/nar/gkaa513. PMID: 32678884.
Congrats to BCDB student Sean Kundinger (Seyfried lab) for his middle author paper published in Cell! Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Arakhamia T, Lee CE, Carlomagno Y, Duong DM, Kundinger SR, Wang K, Williams D, DeTure M, Dickson DW, Cook CN, Seyfried NT, Petrucelli L, Fitzpatrick AWP.Cell. 2020;180(4):633-644.e12. doi: 10.1016/j.cell.2020.01.027. PMID: 32032505
Congrats to BCDB student Maria Sterrett (Corbett lab) for her middle author paper published in PLoS Genetics! A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons. Morton DJ, Jalloh B, Kim L, Kremsky I, Nair RJ, Nguyen KB, Rounds JC, Sterrett MC, Brown B, Le T, Karkare MC, McGaughey KD, Sheng S, Leung SW, Fasken MB, Moberg KH, Corbett AH. PLoS Genet. 2020;16(7):e1008901. doi: 10.1371/journal.pgen.1008901. PMID: 32645003.
Congrats to BCDB student Lee Cato (Ortlund lab) for his co-first author paper published in Bioorg Med Chem Lett! Development of a new class of liver receptor homolog-1 (LRH-1) agonists by photoredox conjugate addition. Cornelison JL, Cato ML, Johnson AM, D'Agostino EH, Melchers D, Patel AB, Mays SG, Houtman R, Ortlund EA, Jui NT. Bioorg Med Chem Lett. 2020;30(16):127293. doi: 10.1016/j.bmcl.2020.127293. PMID: 32631515.
Congrats to BCDB student Sean Kundinger (Seyfried lab) for his middle author paper published in Front Mol Neurosci! Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease. Guo Q, Dammer EB, Zhou M, Kundinger SR, Gearing M, Lah JJ, Levey AI, Shulman JM, Seyfried NT.Front Mol Neurosci. 2021;14:623659. doi: 10.3389/fnmol.2021.623659. PMID: 33815056.
Congrats to BCDB student Emily Bartle (Mattheyses lab) for her first author paper in J Cell Biol! Protein exchange is reduced in calcium-independent epithelial junctions. Bartle EI, Tejeshwar, CR, Beggs RR, Dean WF, Urner TM, Kowalczyk AP, Mattheyses AL. J Cell Biol. 2020; 219(6):e201906153. Doi: 10.1083/jcb.201906153.
Congrats to BCDB student Rachel Turn (Kahn lab) for her first author paper published in Mol Biol Cell! The ARF GAP ELMOD2 acts with different GTPases to regulate centrosomal microtubule nucleation and cytokinesis. Turn RE, East MP, Prekeris R, Kahn RA. Mol Biol Cell. 2020;31(18):2070-2091. doi: 10.1091/mbc.E20-01-0012. PMID: 32614697.
Congrats to BCDB student Skylar Fisher (Kahn lab) for her first author review published in Am J Physiol Cell Physiol! ARF family GTPases with links to cilia. Fisher S, Kuna D, Caspary T, Kahn RA, Sztul E. Am J Physiol Cell Physiol. 2020;319(2):C404-C418. doi: 10.1152/ajpcell.00188.2020. PMID: 32520609.
Congrats to BCDB student Maria Sterrett (Corbett lab) for her middle author review published in Hum Mol Genet! Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness. Slavotinek A, Misceo D, Htun S, Mathisen L, Frengen E, Foreman M, Hurtig JE, Enyenihi L, Sterrett MC, Leung SW, Schneidman-Duhovny D, Estrada-Veras J, Duncan JL, Haaxma CA, Kamsteeg EJ, Xia V, Beleford D, Si Y, Douglas G, Treidene HE, van Hoof A, Fasken MB, Corbett AH. Hum Mol Genet. 2020;29(13):2218-2239. doi: 10.1093/hmg/ddaa108. PMID: 32504085.
Congrats to BCDB student Sabrina Lynn (Koval lab) for her first author review published in Biochim Biophys Acta Biomembr! Ruffles and spikes: Control of tight junction morphology and permeability by claudins. Lynn KS, Peterson RJ, Koval M. Biochim Biophys Acta Biomembr. 2020;1862(9):183339. doi: 10.1016/j.bbamem.2020.183339. PMID: 32389670.
Congrats to BCDB student Alexandra Rha (Lynn lab) for her first author paper published in Angew Chem Int Ed Engl! Electrostatic Complementarity Drives Amyloid/Nucleic Acid Co-Assembly. Rha AK, Das D, Taran O, Ke Y, Mehta AK, Lynn DG. Angew Chem Int Ed Engl. 2020;59(1):358-363. doi: 10.1002/anie.201907661. PMID: 31617300.
2019
Congrats to BCDB student Emma D’Agostino (Ortlund lab) for her first author paper published in ACS Med Chem Lett! Development of a Versatile and Sensitive Direct Ligand Binding Assay for Human NR5A Nuclear Receptors. D'Agostino EH, Flynn AR, Cornelison JL, Mays SG, Patel A, Jui NT, Ortlund EA. ACS Med Chem Lett. 2019;11(3):365-370. doi: 10.1021/acsmedchemlett.9b00442. PMID: 32184971.
Congrats to BCDB student Emily Kuiper (Conn lab) for her first author paper published in JBC! Substrate recognition by the Pseudomonas aeruginosa EF-Tu-modifying methyltransferase EftM. Kuiper EG, Dey D, LaMore PA, Owings JP, Prezioso SM, Goldberg JB, Conn GL. J Biol Chem. 2019;294(52):20109-20121. doi: 10.1074/jbc.RA119.011213. PMID: 31753919.
Congrats to BCDB student Sarah Strassler (Conn lab) and Eric Hoffer (Dunham lab) for their middle author paper published in JBC! Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition. Nosrati M, Dey D, Mehrani A, Strassler SE, Zelinskaya N, Hoffer ED, Stagg SM, Dunham CM, Conn GL. J Biol Chem. 2019;294(46):17642-17653. doi: 10.1074/jbc.RA119.011181. PMID: 31594862.
Congrats to BCDB student Liz Dreggors (Ghalei lab) for her second author paper published in JBC! A conserved Bcd1 interaction essential for box C/D snoRNP biogenesis. Khoshnevis S, Dreggors RE, Hoffmann TFR, Ghalei H. J Biol Chem. 2019;294(48):18360-18371. doi: 10.1074/jbc.RA119.010222. PMID: 31537647.
Congrats to BCDB student Eric Hoffer (Dunham lab) for his middle author paper published in NAR! Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Pavelich IJ, Maehigashi T, Hoffer ED, Ruangprasert A, Miles SJ, Dunham CM. Nucleic Acids Res. 2019;47(19):10400-10413. doi: 10.1093/nar/gkz760. PMID: 31501867.
Congrats to BCDB student Emily Legan (Li lab) for her first author review published in Arterioscler Thromb Vasc Biol! Gone With the Vane. Legan ER, Li R. Arterioscler Thromb Vasc Biol. 2019;39(9):1702-1704. doi: 10.1161/ATVBAHA.119.313110. PMID: 31433699.
Congrats to BCDB student Brenda Calderon (Conn lab) for her first author review published in PLoS Pathogens! Dysregulation of M segment gene expression contributes to influenza A virus host restriction. Calderon BM, Danzy S, Delima GK, Jacobs NT, Ganti K, Hockman MR, Conn GL, Lowen AC, Steel J. PLoS Pathog. 2019;15(8):e1007892. doi: 10.1371/journal.ppat.1007892. PMID: 31415678.
Congrats to BCDB student Lauren Jeffers (Koval lab) for her second author review published in Alcohol! Effects of different routes of endotoxin injury on barrier function in alcoholic lung syndrome. Smith P, Jeffers LA, Koval M. Alcohol. 2019;80:81-89. doi: 10.1016/j.alcohol.2018.08.007. PMID: 31278041.
Congrats to BCDB student Ed Quach (Li lab) for his first author paper published in J Vis Exp! A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry. Quach ME, Syed AK, Li R. J Vis Exp. 2019;(148):10.3791/59704. doi: 10.3791/59704. PMID: 31233025.
Congrats to BCDB student Samantha Schwartz (Conn lab) for her first author review published in Wiley Interdiscip Rev RNA! RNA regulation of the antiviral protein 2'-5'-oligoadenylate synthetase. Schwartz SL, Conn GL. Wiley Interdiscip Rev RNA. 2019;10(4):e1534. doi: 10.1002/wrna.1534. PMID: 30989826.
Congrats to BCDB student Emily Legan (Li lab) for her first author review published in J Thromb Haemost! FAM-tastic phospho-regulation of von Willebrand factor activity. Legan ER, Li R. J Thromb Haemost. 2019;17(6):863-865. doi: 10.1111/jth.14448. PMID: 30985992.
Congrats to BCDB students Rachel Turn and Laura Newman (Kahn lab) for their paper published in Mol Biol Cell! ELMOD2 regulates mitochondrial fusion in a mitofusin-dependent manner, downstream of ARL2. Schiavon CR, Turn RE, Newman LE, Kahn RA. Mol Biol Cell. 2019;30(10):1198-1213. doi: 10.1091/mbc.E18-12-0804. PMID: 30865555.
Congrats to BCDB students Marc Schureck and Eric Hoffer (Dunham lab) for their paper published in Mol Micro! Structural basis of transcriptional regulation by the HigA antitoxin. Schureck MA, Meisner J, Hoffer ED, Wang D, Onuoha N, Ei Cho S, Lollar P 3rd, Dunham CM. Mol Microbiol. 2019;111(6):1449-1462. doi: 10.1111/mmi.14229. PMID: 30793388.
Congrats to BCDB student Eric Hoffer (Dunham lab) for his second author paper published in J JBC! Importance of a tRNA anticodon loop modification and a conserved, noncanonical anticodon stem pairing in tRNAProCGGfor decoding. Nguyen HA, Hoffer ED, Dunham CM. J Biol Chem. 2019;294(14):5281-5291. doi: 10.1074/jbc.RA119.007410. PMID: 30782843.
Congrats to BCDB student Eric Hoffer (Dunham lab) for his first author paper published in NAR! Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding. Hoffer ED, Maehigashi T, Fredrick K, Dunham CM. Nucleic Acids Res. 2019;47(3):1557-1563. doi: 10.1093/nar/gky1178. PMID: 30476222.
2018
Congrats to BCDB student Travis Loya (Reines lab) for his first author paper published in PLoS One! Nab3's localization to a nuclear granule in response to nutrient deprivation is determined by its essential prion-like domain. Loya TJ, O'Rourke TW, Simke WC, Kelley JB, Reines D. PLoS One. 2018;13(12):e0209195. doi: 10.1371/journal.pone.0209195. PMID: 30557374.
Congrats to BCDB student Eric Hoffer (Dunham lab) for his middle author paper published in Inorg Chem! Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors. Rivera S, Young PG, Hoffer ED, Vansuch GE, Metzler CL, Dunham CM, Weinert EE. Inorg Chem. 2018;57(22):14386-14395. doi: 10.1021/acs.inorgchem.8b02584. PMID: 30378421.
Congrats to BCDB student Julia Omotade (Zheng lab) for her first author paper published in J Neurosci! Tropomodulin Isoform-Specific Regulation of Dendrite Development and Synapse Formation. Omotade OF, Rui Y, Lei W, Yu K, Hartzell HC, Fowler VM, Zheng JQ. J Neurosci. 2018;38(48):10271-10285. doi: 10.1523/JNEUROSCI.3325-17.2018. Epub 2018 Oct 9. PMID: 30301754.
Congrats to BCDB student Eric Hoffer (Dunham lab) for his middle author paper published in PNAS! Mechanism of tRNA-mediated +1 ribosomal frameshifting. Hong S, Sunita S, Maehigashi T, Hoffer ED, Dunkle JA, Dunham CM. Proc Natl Acad Sci U S A. 2018;115(44):11226-11231. doi: 10.1073/pnas.1809319115. PMID: 30262649.
Congrats to BCDB student Jarred Whitlock (Hartzell lab) for his first author paper published in J Gen Physiol! Anoctamin 5/TMEM16E facilitates muscle precursor cell fusion. Whitlock JM, Yu K, Cui YY, Hartzell HC. J Gen Physiol. 2018 Nov 5;150(11):1498-1509. doi: 10.1085/jgp.201812097. PMID: 30257928.
Congrats to BCDB student Bredna Calderon (Conn lab) for her first author paper published in JBC! A human cellular noncoding RNA activates the antiviral protein 2'-5'-oligoadenylate synthetase 1. Calderon BM, Conn GL. J Biol Chem. 2018;293(41):16115-16124. doi: 10.1074/jbc.RA118.004747. PMID: 30126839.
Congrats to BCDB student Emily Weikum (Ortlund lab) for her first author review published in Protein Sci! The nuclear receptor superfamily: A structural perspective. Weikum ER, Liu X, Ortlund EA. Protein Sci. 2018;27(11):1876-1892. doi: 10.1002/pro.3496. PMID: 30109749.
Congrats to BCDB student Kevin Morris (Corbett lab) for his first author paper published in NAR! The polyadenosine RNA-binding protein ZC3H14 interacts with the THO complex and coordinately regulates the processing of neuronal transcripts. Morris KJ, Corbett AH. Nucleic Acids Res. 2018;46(13):6561-6575. doi: 10.1093/nar/gky446. PMID: 29912477.
Congrats to BCDB student Isaac Bishof (Seyfried lab) for his first author paper published in JBC! RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease. Bishof I, Dammer EB, Duong DM, Kundinger SR, Gearing M, Lah JJ, Levey AI, Seyfried NT. J Biol Chem. 2018;293(28):11047-11066. doi: 10.1074/jbc.RA118.001747. PMID: 29802200.
Congrats to BCDB student Dawn Barnes (Ono lab) for her first author paper published in Mol Biol Cell! Tropomyosin isoforms differentially affect muscle contractility in the head and body regions of the nematode Caenorhabditis elegans. Barnes DE, Watabe E, Ono K, Kwak E, Kuroyanagi H, Ono S. Mol Biol Cell. 2018;29(9):1075-1088. doi: 10.1091/mbc.E17-03-0152. PMID: 29496965.
Congrats to BCDB student Ed Quach (Li lab) for his first author review published in Blood! Mechanisms of platelet clearance and translation to improve platelet storage. Quach ME, Chen W, Li R. Blood. 2018;131(14):1512-1521. doi: 10.1182/blood-2017-08-743229. PMID: 29475962.
Congrats to BCDB student Emily Hunter (Sale lab) for her first author paper published in Mol Biol Cell! The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length. Hunter EL, Lechtreck K, Fu G, Hwang J, Lin H, Gokhale A, Alford LM, Lewis B, Yamamoto R, Kamiya R, Yang F, Nicastro D, Dutcher SK, Wirschell M, Sale WS. Mol Biol Cell. 2018;29(8):886-896. doi: 10.1091/mbc.E17-12-0729. PMID: 29467251.
Congrats to BCDB student Alicia Cutler (Corbett & Pavlath lab) for her first author paper published in J Cell Sci! Non-equivalence of nuclear import among nuclei in multinucleated skeletal muscle cells. Cutler AA, Jackson JB, Corbett AH, Pavlath GK. J Cell Sci. 2018;131(3):jcs207670. doi: 10.1242/jcs.207670. PMID: 29361530.
Congrats to BCDB student Kelsey Maher (Deal lab) for her first author paper published in Plant Cell! Profiling of Accessible Chromatin Regions across Multiple Plant Species and Cell Types Reveals Common Gene Regulatory Principles and New Control Modules. Maher KA, Bajic M, Kajala K, Reynoso M, Pauluzzi G, West DA, Zumstein K, Woodhouse M, Bubb K, Dorrity MW, Queitsch C, Bailey-Serres J, Sinha N, Brady SM, Deal RB. Plant Cell. 2018;30(1):15-36. doi: 10.1105/tpc.17.00581. PMID: 29229750.
Congrats to BCDB student Ed Quach (Li lab) for his first author paper published in Blood! Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets. Quach ME, Dragovich MA, Chen W, Syed AK, Cao W, Liang X, Deng W, De Meyer SF, Zhu G, Peng J, Ni H, Bennett CM, Hou M, Ware J, Deckmyn H, Zhang XF, Li R. Blood. 2018;131(7):787-796. doi: 10.1182/blood-2017-05-784975. PMID: 29203584.
2017
Congrats to BCDB student Emily Bartle (Mattheyses lab) for her first author paper in Biophysical Journal! Desmoglein 3 Order and Dynamics in Desmosomes Determined by Fluorescence Polarization Microscopy. Bartle EI, Urner TM, Raju SS, and Mattheyses AL. Biophysical journal. 2017:113:2519-2529.
Congrats to BCDB student Emily Bartle (Mattheyses lab) for her first author paper in Tissues Barrier! Bridging the gap: super-resolution microscopy of epithelial cell junctions. Bartle EI, Rao TC, Urner TM, and Mattheyses AL. Tissue Barriers. 2017:6(1):e1404189. doi: 10.1080/21688370.2017.1404189.
Congrats to BCDB student Alicia Cutler (Corbett & Pavlath labs) for her first author paper published in Bio Protoc! Biochemical Isolation of Myonuclei from Mouse Skeletal Muscle Tissue. Cutler AA, Corbett AH, Pavlath GK. Bio Protoc. 2017;7(24):e2654. doi: 10.21769/BioProtoc.2654. PMID: 29594187.
Congrats to BCDB student Travis Loya (Reines lab) for his first author paper published in PLoS One! The hnRNP-like Nab3 termination factor can employ heterologous prion-like domains in place of its own essential low complexity domain. Loya TJ, O'Rourke TW, Reines D. PLoS One. 2017;12(10):e0186187. doi: 10.1371/journal.pone.0186187. PMID: 29023495.
Congrats to BCDB student Josh Francis (Kahn lab) for his first author paper published in JMB! Nucleotide Binding to ARL2 in the TBCD∙ARL2∙β-Tubulin Complex Drives Conformational Changes in β-Tubulin. Francis JW, Goswami D, Novick SJ, Pascal BD, Weikum ER, Ortlund EA, Griffin PR, Kahn RA. J Mol Biol. 2017;429(23):3696-3716. doi: 10.1016/j.jmb.2017.09.016. PMID: 28970104.
Congrats to BCDB student Laura Newman (Kahn lab) for her first author paper published in Cell Logist! The ARL2 GTPase regulates mitochondrial fusion from the intermembrane space. Newman LE, Schiavon CR, Turn RE, Kahn RA. Cell Logist. 2017;7(3):e1340104. doi: 10.1080/21592799.2017.1340104. PMID: 28944094.
Congrats to BCDB student Andrew Bankston (Feng lab) for his first author paper published in Bio Protoc! Active Cdk5 Immunoprecipitation and Kinase Assay. Bankston AN, Ku L, Feng Y. Bio Protoc. 2017;7(13):e2363. doi: 10.21769/BioProtoc.2363. PMID: 28868329.
Congrats to BCDB student Amanda York (Zheng lab) for her first author paper published in eNeuro! Super-Resolution Microscopy Reveals a Nanoscale Organization of Acetylcholine Receptors for Trans-Synaptic Alignment at Neuromuscular Synapses. York AL, Zheng JQ. eNeuro. 2017;4(4):ENEURO.0232-17.2017. doi: 10.1523/ENEURO.0232-17.2017. PMID: 28798955.
Congrats to BCDB student Rasagnya Viswanadha (Sale lab) for her first author review published in Cold Spring Harb Perspect Biol! Ciliary Motility: Regulation of Axonemal Dynein Motors. Viswanadha R, Sale WS, Porter ME. Cold Spring Harb Perspect Biol. 2017;9(8):a018325. doi: 10.1101/cshperspect.a018325. PMID: 28765157
Congrats to BCDB student Jen Rha (Corbett lab) for her first author review published in Hum Mol Genet! The RNA-binding protein, ZC3H14, is required for proper poly(A) tail length control, expression of synaptic proteins, and brain function in mice. Rha J, Jones SK, Fidler J, Banerjee A, Leung SW, Morris KJ, Wong JC, Inglis GAS, Shapiro L, Deng Q, Cutler AA, Hanif AM, Pardue MT, Schaffer A, Seyfried NT, Moberg KH, Bassell GJ, Escayg A, García PS, Corbett AH. Hum Mol Genet. 2017;26(19):3663-3681. doi: 10.1093/hmg/ddx248. PMID: 28666327.
Congrats to BCDB student Emily Weikum (Ortlund lab) for her first author paper published in NAR! Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes. Weikum ER, de Vera IMS, Nwachukwu JC, Hudson WH, Nettles KW, Kojetin DJ, Ortlund EA. Nucleic Acids Res. 2017;45(14):8596-8608. doi: 10.1093/nar/gkx509. PMID: 28591827.
Congrats to BCDB student Skylar Fisher (Hartzell lab) for her first author review published in eLife! Poring over furrows. Fisher SI, Hartzell HC. Elife. 2017;6:e27933. doi: 10.7554/eLife.27933. PMID: 28561734.
Congrats to BCDB student Alicia Cutler (Corbett & Pavlath labs) for her first author paper published in Aging Cell! Biochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging. Cutler AA, Dammer EB, Doung DM, Seyfried NT, Corbett AH, Pavlath GK. Aging Cell. 201716(4):738-749. doi: 10.1111/acel.12604. PMID: 28544616.
Congrats to BCDB student Emily Weikum (Ortlund lab) for her first author paper published in Mol Pharmacol! Structural Analysis of the Glucocorticoid Receptor Ligand-Binding Domain in Complex with Triamcinolone Acetonide and a Fragment of the Atypical Coregulator, Small Heterodimer Partner. Weikum ER, Okafor CD, D'Agostino EH, Colucci JK, Ortlund EA. Mol Pharmacol. 2017;92(1):12-21. doi: 10.1124/mol.117.108506. PMID: 28396564.
Congrats to BCDB student Laura Newman (Kahn lab) for her first author paper published in Mol Pharmacol! The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors. Newman LE, Schiavon CR, Zhou C, Kahn RA. PLoS One. 2017;12(4):e0175164. doi: 10.1371/journal.pone.0175164. PMID: 28380071.
Congrats to BCDB student Sky Comstra (Faundez lab) for her first author paper published in eLife! The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors. Comstra HS, McArthy J, Rudin-Rush S, Hartwig C, Gokhale A, Zlatic SA, Blackburn JB, Werner E, Petris M, D'Souza P, Panuwet P, Barr DB, Lupashin V, Vrailas-Mortimer A, Faundez V. Elife. 2017;6:e24722. doi: 10.7554/eLife.24722. PMID: 28355134.
Congrats to BCDB student Eric Hoffer (Dunham lab) for his first author paper published in JBC! The structure and function of Mycobacterium tuberculosis MazF-mt6 toxin provide insights into conserved features of MazF endonucleases. Hoffer ED, Miles SJ, Dunham CM. J Biol Chem. 2017;292(19):7718-7726. doi: 10.1074/jbc.M117.779306. PMID: 28298445.
Congrats to BCDB student Paul Donlin-Asp (Bassell lab) for his first author paper published in FEBS Lett! Spatially and temporally regulating translation via mRNA-binding proteins in cellular and neuronal function. Donlin-Asp PG, Rossoll W, Bassell GJ. FEBS Lett. 2017;591(11):1508-1525. doi: 10.1002/1873-3468.12621. PMID: 28295262.
Congrats to BCDB student Julia Omotade (Zheng lab) for her first author review published in Mol Cell Neurosci! Actin-based growth cone motility and guidance. Omotade OF, Pollitt SL, Zheng JQ. Mol Cell Neurosci. 2017;84:4-10. doi: 10.1016/j.mcn.2017.03.001. PMID: 28268126.
Congrats to BCDB student Paul Donlin-Asp (Bassell lab) for his first author paper published in Cell Rep! The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly. Donlin-Asp PG, Fallini C, Campos J, Chou CC, Merritt ME, Phan HC, Bassell GJ, Rossoll W. Cell Rep. 2017;18(7):1660-1673. doi: 10.1016/j.celrep.2017.01.059. PMID: 28199839.
Congrats to BCDB student Josh Francis (Kahn lab) for his first author paper published in JBC! A Trimer Consisting of the Tubulin-specific Chaperone D (TBCD), Regulatory GTPase ARL2, and β-Tubulin Is Required for Maintaining the Microtubule Network. Francis JW, Newman LE, Cunningham LA, Kahn RA. J Biol Chem. 2017;292(10):4336-4349. doi: 10.1074/jbc.M116.770909. PMID: 28126905.
Congrats to BCDB student Brenda Calderon (Conn lab) for her first author paper published in RNA! Human noncoding RNA 886 (nc886) adopts two structurally distinct conformers that are functionally opposing regulators of PKR. Calderon BM, Conn GL. RNA. 2017;23(4):557-566. doi: 10.1261/rna.060269.116. PMID: 28069888.
Congrats to BCDB student Emily Weikum (Ortlund lab) for her first author review published in Nat Rev Mol Cell Biol! Glucocorticoid receptor control of transcription: precision and plasticity via allostery. Weikum ER, Knuesel MT, Ortlund EA, Yamamoto KR. Nat Rev Mol Cell Biol. 2017;18(3):159-174. doi: 10.1038/nrm.2016.152. PMID: 28053348
Congrats to BCDB student Emily Kuiper (Conn lab) for her second author paper published in JBC! A Novel Motif for S-Adenosyl-l-methionine Binding by the Ribosomal RNA Methyltransferase TlyA from Mycobacterium tuberculosis. Witek MA, Kuiper EG, Minten E, Crispell EK, Conn GL. J Biol Chem. 2017;292(5):1977-1987. doi: 10.1074/jbc.M116.752659. PMID: 28031456.
2016
Congrats to BCDB student Laura Newman (Kahn lab) for her first author paper published in Cell Logist! Plasmids for variable expression of proteins targeted to the mitochondrial matrix or intermembrane space. Newman LE, Schiavon C, Kahn RA. Cell Logist. 2016;13;6(4):e1247939. doi: 10.1080/21592799.2016.1247939. PMID: 28042516.
Congrats to BCDB student Emily Weikum (Ortlund lab) for her first author paper published in JMB! A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF), and Liver Receptor Homolog-1 (LRH-1). Weikum ER, Tuntland ML, Murphy MN, Ortlund EA. J Mol Biol. 2016;428(24 Pt B):4981-4992. doi: 10.1016/j.jmb.2016.10.025. PMID: 27984042
Congrats to BCDB student Jarred Whitlock (Hartzell lab) for his first author review published in Annu Rev Physiol! Anoctamins/TMEM16 Proteins: Chloride Channels Flirting with Lipids and Extracellular Vesicles. Whitlock JM, Hartzell HC. Annu Rev Physiol. 2017;79:119-143. doi: 10.1146/annurev-physiol-022516-034031. PMID: 27860832.
Congratulations to BCDB student Sara Stahley (Kowalczyk lab) for publishing a first author paper in the Journal of Investigative Dermatology! Super-Resolution Microscopy Reveals Altered Desmosomal Protein Organization in Tissue from Patients with Pemphigus Vulgaris. Stahley SN, Warren MF, Feldman RJ, Swerlick RA, Mattheyses AL, Kowalczyk AP. J Invest Dermatol. 2016: 136(1):59-66. doi: 10.1038/JID.2015.353. PMID: 26763424
Congrats to BCDB student Jarred Whitlock (Hartzell lab) for his second author review published in J Gen Physiol! TMEM16 chloride channels are two-faced. Hartzell HC, Whitlock JM. J Gen Physiol. 2016;148(5):367-373. doi: 10.1085/jgp.201611686. PMID: 27799317.
Congrats to BCDB student Shea Cadwell (Kowalczyk lab) for her first author review in Traffic! Cadherin Tales: Regulation of Cadherin Function by Endocytic Membrane Trafficking. Cadwell CM, Su W, Kowalczyk AP. Traffic. 2016:17(12):1262-71. doi: 10.1111/tra.12448. PMID:27624909.
Congrats to BCDB student Shea Cadwell (Kowalczyk lab) for her first author paper in JBC! Ankyrin-G Inhibits Endocytosis of Cadherin Dimers. Cadwell CM, Jenkins PM, Bennett V, Kowalczyk AP. J Biol Chem. 2016:291(2):691-704. doi: 10.1074/jbc.M115.648386. PMID: 26574545.
Congrats to BCDB student Eric Hoffer (Dunham lab) for his second author paper published in Cell Rep! Uniformity of Peptide Release Is Maintained by Methylation of Release Factors. Pierson WE, Hoffer ED, Keedy HE, Simms CL, Dunham CM, Zaher HS. Cell Rep. 2016;17(1):11-18. doi: 10.1016/j.celrep.2016.08.085. PMID: 27681416.
Congrats to BCDB student Jadiel Wasson (Katz lab) who published a first author paper in eLife! Maternally provided LSD1/KDM1A enables the maternal-to-zygotic transition and prevents defects that manifest postnatally. Wasson JA, Simon AK, Myrick DA, Wolf G, Driscoll S, Pfaff SL, Macfarlan TS, Katz DJ. eLife 2016:5. pii: e08848. doi: 10.7554/eLife.08848.
Congrats to BCDB student Callie Wigington and Kevin Morris (Corbett lab) for their paper published in JBC! The Polyadenosine RNA-binding Protein, Zinc Finger Cys3His Protein 14 (ZC3H14), Regulates the Pre-mRNA Processing of a Key ATP Synthase Subunit mRNA. Wigington CP, Morris KJ, Newman LE, Corbett AH. J Biol Chem. 2016;291(43):22442-22459. doi: 10.1074/jbc.M116.754069. PMID: 27563065.
Congrats to BCDB student Sharon Soucek (Corbett lab) for her first author paper published in Mol Cell Biol! The Evolutionarily-conserved Polyadenosine RNA Binding Protein, Nab2, Cooperates with Splicing Machinery to Regulate the Fate of pre-mRNA. Soucek S, Zeng Y, Bellur DL, Bergkessel M, Morris KJ, Deng Q, Duong D, Seyfried NT, Guthrie C, Staley JP, Fasken MB, Corbett AH. Mol Cell Biol. 2016;36(21):2697-2714. doi: 10.1128/MCB.00402-16. PMID: 27528618.
Congrats to BCDB student Emily Hunter (Sale lab) for her first author paper published in Methods Mol Biol! Analysis of Axonemal Assembly During Ciliary Regeneration in Chlamydomonas. Hunter EL, Sale WS, Alford LM. Methods Mol Biol. 2016;1454:237-43. doi: 10.1007/978-1-4939-3789-9_15. PMID: 27514926.
Congrats to BCDB student Jessie Hwang (Pallas lab) for her first author review published in JBC! Leucine Carboxyl Methyltransferase 1 (LCMT-1) Methylates Protein Phosphatase 4 (PP4) and Protein Phosphatase 6 (PP6) and Differentially Regulates the Stable Formation of Different PP4 Holoenzymes. Hwang J, Lee JA, Pallas DC. J Biol Chem. 2016;291(40):21008-21019. doi: 10.1074/jbc.M116.739920. PMID: 27507813.
Congrats to BCDB student Travis Loya (Reines lab) for his first author review published in F1000Res! Recent advances in understanding transcription termination by RNA polymerase II. Loya TJ, Reines D. F1000Res. 2016;5:F1000 Faculty Rev-1478. doi: 10.12688/f1000research.8455.1. PMID: 27408690
Congrats to BCDB student Josh Francis (Kahn lab) for his first author paper published in Small GTPases! Higher order signaling: ARL2 as regulator of both mitochondrial fusion and microtubule dynamics allows integration of 2 essential cell functions. Francis JW, Turn RE, Newman LE, Schiavon C, Kahn RA. Small GTPases. 2016;7(4):188-196. doi: 10.1080/21541248.2016.1211069. PMID: 27400436
Congrats to BCDB student Marc Schureck (Dunham lab) for his first author paper published in NAR! Mechanism of endonuclease cleavage by the HigB toxin. Schureck MA, Repack A, Miles SJ, Marquez J, Dunham CM. Nucleic Acids Res. 2016;44(16):7944-53. doi: 10.1093/nar/gkw598. PMID: 27378776.
Congrats to BCDB student Marc Schureck (Dunham lab) for his first author paper published in RNA! mRNA bound to the 30S subunit is a HigB toxin substrate. Schureck MA, Maehigashi T, Miles SJ, Marquez J, Dunham CM. RNA. 2016;22(8):1261-70. doi: 10.1261/rna.056218.116. PMID: 27307497.
Congrats to BCDB student Paul Donlin-Asp (Bassell lab) for his first author review published in Curr Opim Neurobiol! A role for the survival of motor neuron protein in mRNP assembly and transport. Donlin-Asp PG, Bassell GJ, Rossoll W. Curr Opin Neurobiol. 2016;39:53-61. doi: 10.1016/j.conb.2016.04.004. PMID: 27131421.
Congrats to BCDB student Shana Kerr (Kahn lab) for her first author paper published in Cell Logist! Tool box: Plasmids for the expression or knockdown of human ARF Family GTPases (ARF/ARL/SAR) and their co-expression in bacteria with N-myristoyltransferases. Kerr SC, Kahn RA. Cell Logist. 2015;5(3):e1090523. doi: 10.1080/21592799.2015.1090523. PMID: 27057421.
Congrats to BCDB student Danny Barron (Moberg lab) for his first author paper published in Sci Rep! Inverse regulation of two classic Hippo pathway target genes in Drosophila by the dimerization hub protein Ctp. Barron DA, Moberg K. Sci Rep. 2016;6:22726. doi: 10.1038/srep22726. PMID: 26972460.
Congrats to BCDB student Dawn Barnes (Ono lab) for her first author paper published in Cytoskeleton! Molecular evolution of troponin I and a role of its N-terminal extension in nematode locomotion. Barnes DE, Hwang H, Ono K, Lu H, Ono S. Cytoskeleton (Hoboken). 2016;73(3):117-30. doi: 10.1002/cm.21281. PMID: 26849746.
Congrats to BCDB student Jarred Whitlock (Hartzell lab) for his first author paper published in Pflugers Arch! A Pore Idea: the ion conduction pathway of TMEM16/ANO proteins is composed partly of lipid. Whitlock JM, Hartzell HC. Pflugers Arch. 2016 Mar;468(3):455-73. doi: 10.1007/s00424-015-1777-2. PMID: 26739711.
Congrats to BCDB student Emily Kuiper (Conn lab) for her second author paper published in JBC! Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase. Owings JP, Kuiper EG, Prezioso SM, Meisner J, Varga JJ, Zelinskaya N, Dammer EB, Duong DM, Seyfried NT, Albertí S, Conn GL, Goldberg JB. J Biol Chem. 2016;291(7):3280-90. doi: 10.1074/jbc.M115.706853. PMID: 26677219.
Congrats to BCDB student Katie Williams (Bassell lab) for her first author paper published in Mol Biol Cell! hnRNP-Q1 represses nascent axon growth in cortical neurons by inhibiting Gap-43 mRNA translation. Williams KR, McAninch DS, Stefanovic S, Xing L, Allen M, Li W, Feng Y, Mihailescu MR, Bassell GJ. Mol Biol Cell. 2016;27(3):518-34. doi: 10.1091/mbc.E15-07-0504. PMID: 26658614.
Congrats to BCDB student Seth Kelly (Moberg lab) for his first author paper published in Dev Neurobiol! The Drosophila ortholog of the Zc3h14 RNA binding protein acts within neurons to pattern axon projection in the developing brain. Kelly SM, Bienkowski R, Banerjee A, Melicharek DJ, Brewer ZA, Marenda DR, Corbett AH, Moberg KH. Dev Neurobiol. 2016 Jan;76(1):93-106. doi: 10.1002/dneu.22301. PMID: 25980665.
2015
Congrats to BCDB student Nick Bauer (Doetsch & Corbett labs) for his first author paper published in NAR! The current state of eukaryotic DNA base damage and repair. Bauer NC, Corbett AH, Doetsch PW. Nucleic Acids Res. 2015;43(21):10083-101. doi: 10.1093/nar/gkv1136. PMID: 26519467.
Congrats to BCDB student Marc Schureck (Dunham lab) for his first author paper published in PNAS! Defining the mRNA recognition signature of a bacterial toxin protein. Schureck MA, Dunkle JA, Maehigashi T, Miles SJ, Dunham CM. Proc Natl Acad Sci U S A. 2015;112(45):13862-7. doi: 10.1073/pnas.1512959112. PMID: 26508639
Congrats to BCDB student Matt Randolph (Pavlath lab) for his first author paper published in Stem Cells! Pharyngeal Satellite Cells Undergo Myogenesis Under Basal Conditions and Are Required for Pharyngeal Muscle Maintenance. Randolph ME, Phillips BL, Choo HJ, Vest KE, Vera Y, Pavlath GK. Stem Cells. 2015;33(12):3581-95. doi: 10.1002/stem.2098. PMID: 26178867.
Congrats to BCDB student Nick Bauer (Doetsch & Corbett labs) for his first author review published in Traffic! Mechanisms Regulating Protein Localization. Bauer NC, Doetsch PW, Corbett AH. Traffic. 2015;16(10):1039-61. doi: 10.1111/tra.12310. PMID: 26172624.
Congrats to BCDB student Eric Hoffer (Dunham lab) for his middle author paper published in Nat Comm! Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase. Cruz JW, Sharp JD, Hoffer ED, Maehigashi T, Vvedenskaya IO, Konkimalla A, Husson RN, Nickels BE, Dunham CM, Woychik NA. Nat Commun. 2015;6:7480. doi: 10.1038/ncomms8480. PMID: 26158745.
Congrats to BCDB student Callie Wigington (Corbett lab) for her first author paper published in JBC! Post-transcriptional regulation of programmed cell death 4 (PDCD4) mRNA by the RNA-binding proteins human antigen R (HuR) and T-cell intracellular antigen 1 (TIA1). Wigington CP, Jung J, Rye EA, Belauret SL, Philpot AM, Feng Y, Santangelo PJ, Corbett AH. J Biol Chem. 2015;290(6):3468-87. doi: 10.1074/jbc.M114.631937. PMID: 25519906.
Congrats to BCDB student Kevin Van Bortle (Corces lab) for his first author paper in RNA! Integrated tRNA, transcript, and protein profiles in response to steroid hormone signaling. Van Bortle K, Nichols MH, Ramos E, Corces VG. RNA. (2015:21(10):1807-17. doi: 10.1261/rna.052126.115. PMID: 26289344.
Congrats to BCDB student Sara Stahley (Kowalczyk lab) for her first author review in the Cell Tissue Research! Desmosomes in acquired disease. Stahley SN, Kowalczyk AP. Cell Tissue Res. 2015:360(3):439-56. doi: 10.1007/s00441-015-2155-2. PMID: 25795143.
Congrats to BCDB student Kevin Van Bortle (Corces lab) for his first author paper in Cell Cycle! CTCF-dependent co-localization of canonical Smad signaling factors at architectural protein binding sites in D. melanogaster. Van Bortle K, Peterson AJ, Takenaka N, O'Connor MB, Corces VG. Cell Cycle. 2015:14(16):2677-87. doi: 10.1080/15384101.2015.1053670. PMID: 26125535
2014
Congrats to BCDB student Laura Newman (Kahn lab) for her first author paper in PLoS One! The ARL2 GTPase is required for mitochondrial morphology, motility, and maintenance of ATP levels. Newman LE, Zhou CJ, Mudigonda S, Mattheyses AL, Paradies E, Marobbio CM, Kahn RA. 2014:9(6):e99270. doi: 10.1371/journal.pone.0099270. PMID: 24911211.
Congrats to BCDB student Kevin Van Bortle (Corces lab) for his first author paper in Genome Biology! Insulator function and topological domain border strength scale with architectural protein occupancy. Van Bortle K, Nichols MH, Li L, Ong CT, Takenaka N, Qin ZS, Corces VG. Genome Biol. 2014:15(6):R82. doi: 10.1186/gb-2014-15-5-r82. PMID: 24981874.
Congrats to BCDB student Crys Fagan (Dunham lab) for her first author paper in RNA! Structural insights into translational recoding by frameshift suppressor tRNASufJ. Fagan CE, Maehigashi T, Dunkle JA, Miles SJ, Dunham CM. RNA. 2014: 20(12):1944-54. doi: 10.1261/rna.046953.114. PMID: 25352689.
Congrats to BCDB student Matthew Randolph (Pavlath lab) for his first author paper in Journal of Physiology! Ageing and muscular dystrophy differentially affect murine pharyngeal muscles in a region-dependent manner. Randolph ME, Luo Q, Ho J, Vest KE, Sokoloff AJ, Pavlath GK. J Physiol. 2014:592(23):5301-15. doi: 10.1113/jphysiol.2014.280420. PMID: 25326455.
Congrats to BCDB student Callie Wigington (Corbett lab) for her first author review in Wiley Interdisciplnary Reviews of RNA! Poly(A) RNA-binding proteins and polyadenosine RNA: new members and novel functions. Wigington CP, Williams KR, Meers MP, Bassell GJ, Corbett AH. Wiley Interdiscip Rev RNA. 2014:5(5):601-22. doi: 10.1002/wrna.1233. PMID: 24789627.
Congrats to BCDB student Rasagna Viswandha (Sale lab) for her first author paper in Cytoskeleton! The ciliary inner dynein arm, I1 dynein, is assembled in the cytoplasm and transported by IFT before axonemal docking. Viswanadha R, Hunter EL, Yamamoto R, Wirschell M, Alford LM, Dutcher SK, Sale WS. Cytoskeleton (Hoboken). 2014:71(10):573-86. doi: 10.1002/cm.21192. PMID: 25252184.
Congrats to BCDB student Chelsey Ruppersburg (Hartzell lab) for her first author paper in Molecular Biology of the Cell! The Ca2+-activated Cl- channel ANO1/TMEM16A regulates primary ciliogenesis. Ruppersburg CC, Hartzell HC. Mol Biol Cell. 2014:25(11):1793-807. doi: 10.1091/mbc.E13-10-0599. PMID: 24694595.
Congrats to BCDB student Emily Kuiper (Conn lab) for her first author paper in Journal of Biological Chemistry! Binding induced RNA conformational changes control substrate recognition and catalysis by the thiostrepton resistance methyltransferase (Tsr). Kuiper EG, Conn GL. J Biol Chem. 2014:289(38):26189-200. doi: 10.1074/jbc.M114.574780. PMID: 25086036.
Congrats to BCDB student Marc Schureck (Dunham lab) for his first author paper in Journal of Biological Chemistry! Structure of the Proteus vulgaris HigB-(HigA)2-HigB toxin-antitoxin complex. Schureck MA, Maehigashi T, Miles SJ, Marquez J, Cho SE, Erdman R, Dunham CM. J Biol Chem. 2014:289(2):1060-70. doi: 10.1074/jbc.M113.512095. PMID: 24257752.
Congrats to BCDB student Mariana Mandler (Feng lab) for her first author paper in Nucleic Acids Research! A cytoplasmic quaking I isoform regulates the hnRNP F/H-dependent alternative splicing pathway in myelinating glia. Mandler MD, Ku L, Feng Y. Nucleic Acids Res. 2014:42(11):7319-29. doi: 10.1093/nar/gku353. PMID: 24792162.
Congrats to BCDB student Jessie Hwang (Pallas lab) for her first author review in the International Journal of Biochemistry & Cell Biology! STRIPAK complexes: structure, biological function, and involvement in human diseases. Hwang J, Pallas DC. (Int J Biochem Cell Biol. 2014:47:118-48. doi: 10.1016/j.biocel.2013.11.021. PMID: 24333164.
Congrats to BCDB student Sara Stahley f(Kowalczyk lab) her first author paper in PLoS One! Desmosome assembly and disassembly are membrane raft-dependent. Stahley SN, Saito M, Faundez V, Koval M, Mattheyses AL, Kowalczyk AP. PLoS One. 2014:9(1):e87809. doi: 10.1371/journal.pone.0087809. PMID: 24498201.
2013
Congrats to BCDB student Jadiel Wasson (Katz lab) for her first author review in Briefings in Functional Genomics! Restoring totipotency through epigenetic reprogramming. Wasson JA, Ruppersburg CC, Katz DJ. Brief Funct Genomics 2013:12(2):118-28. doi: 10.1093/bfgp/els042. PMID:23117862.
Congrats to BCDB student Jen Colucci (Ortlund lab) for her first author paper in PLoS One! X-ray crystal structure of the ancestral 3-ketosteroid receptor-progesterone-mifepristone complex shows mifepristone bound at the coactivator binding interface. Colucci JK, Ortlund EA. PLoS One 2013:8(11):e80761. doi: 10.1371/journal.pone.0080761. PMID: 24260475.
Congrats to BCDB student John Lattier (Grossniklaus lab) for his first author paper in Clinical and Experimental Metastasis! Host pigment epithelium-derived factor (PEDF) prevents progression of liver metastasis in a mouse model of uveal melanoma. Lattier JM, Yang H, Crawford S, Grossniklaus HE. Clin Exp Metastasis. 2013:30(8):969-76. doi: 10.1007/s10585-013-9596-3. PMID: 23793989.
Congrats to BCDB student Crys Fagan (Dunham lab) for her first author paper in PNAS! Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state. Fagan CE, Dunkle JA, Maehigashi T, Dang MN, Devaraj A, Miles SJ, Qin D, Fredrick K, Dunham CM. Proc Natl Acad Sci U S A. 2013: 110(24):9716-21. doi: 10.1073/pnas.1301585110. PMID: 23630274
Congrats to BCDB student Megan Allen (Feng lab) for her first author paper in PLoS One! HuD promotes BDNF expression in brain neurons via selective stabilization of the BDNF long 3'UTR mRNA. Allen M, Bird C, Feng W, Liu G, Li W, Perrone-Bizzozero NI, Feng Y. PLoS One. 2013: 8(1):e55718. doi: 10.1371/journal.pone.0055718. PMID: 23383270
Congrats to BCDB student Kevin Van Bortle (Corces lab) for his first author review in Cell! Spinning the web of cell fate. Van Bortle K, Corces VG. Cell. 2013:14;152(6):1213-7. doi: 10.1016/j.cell.2013.02.052. PMID: 23498930.
Congrats to BCDB student Nick Bauer (Doetsch lab) for his first author paper in Traffic! Automated quantification of the subcellular localization of multicompartment proteins via Q-SCAn. Bauer NC, Corbett AH, Doetsch PW. Traffic. 2013:14(12):1200-8. doi: 10.1111/tra.12118. PMID: 24034606
Congrats to BCDB student Robert Rankin (Nusrat lab) for publishing a first author paper in Journal of Biological Chemistry! Annexin A2 regulates β1 integrin internalization and intestinal epithelial cell migration. Rankin CR, Hilgarth RS, Leoni G, Kwon M, Den Beste KA, Parkos CA, Nusrat A. J Biol Chem. 2013:288(21):15229-39. doi: 10.1074/jbc.M112.440909. PMID: 23558678.
Congrats to BCDB student Kevin Van Bortle (Corces lab) for his first author review in Current Opinion in Genetics & Development! The role of chromatin insulators in nuclear architecture and genome function. Van Bortle K, Corces VG. Curr Opin Genet Dev. 2013:23(2):212-8. doi: 10.1016/j.gde.2012.11.003. PMID: 23298659.
Congrats to BCDB student Jen Colucci (Ortlund lab) for her first author paper in Acta Crystallographica! Expression, purification and crystallization of the ancestral androgen receptor-DHT complex. Colucci JK, Ortlund EA. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013;69(Pt 9):994-6. doi: 10.1107/S1744309113018745. PMID: 23989146
2012
Congrats to BCDB student Kevin Van Bortle (Corces lab) for his first author review in Transcription! tDNA insulators and the emerging role of TFIIIC in genome organization. Van Bortle K, Corces VG. Transcription. 2012: 3(6):277-84. doi: 10.4161/trns.21579. PMID: 22889843
Congrats to BCDB student Mike East (Kahn lab) for his first author paper in Journal of Biological Chemistry! ELMO domains, evolutionary and functional characterization of a novel GTPase-activating protein (GAP) domain for Arf protein family GTPases. East MP, Bowzard JB, Dacks JB, Kahn RA. (2012). J Biol Chem. 2012: 287(47):39538-53. doi: 10.1074/jbc.M112.417477. PMID: 23014990
Congrats to BCDB student Ben Nanes (Kowalczyk lab) for his first author paper in the Journal of Cell Biology! p120-catenin binding masks an endocytic signal conserved in classical cadherins. Nanes BA, Chiasson-MacKenzie C, Lowery AM, Ishiyama N, Faundez V, Ikura M, Vincent PA, Kowalczyk AP. J Cell Biol. 2012: 199(2):365-80. doi: 10.1083/jcb.201205029. PMID: 23071156
Congrats to BCDB student Kevin Van Bortle (Corces lab) for his first author paper in Genome Biology! Drosophila CTCF tandemly aligns with other insulator proteins at the borders of H3K27me3 domains. Van Bortle K, Ramos E, Takenaka N, Yang J, Wahi JE, Corces VG. Genome Res. 2012: 22(11):2176-87. doi: 10.1101/gr.136788.111. PMID: 22722341
Congrats to BCDB student Sharon Soucek (Corbett lab) for her first author review in Biochimica et Biophysica Acta! The long and the short of it: the role of the zinc finger polyadenosine RNA binding protein, Nab2, in control of poly(A) tail length. Soucek S, Corbett AH, Fasken MB. Biochim Biophys Acta. 2012: 1819(6):546-54. doi: 10.1016/j.bbagrm.2012.03.006. PMID: 22484098.
Congrats to BCDB student Kevin Van Bortle (Corces lab) for his first author review in Annual Reviews in Cell & Developmental Biology! Nuclear organization and genome function. Van Bortle K, Corces VG. Annu Rev Cell Dev Biol. 2012: 28:163-87. doi: 10.1146/annurev-cellbio-101011-155824. PMID: 22905954.
Congrats to BCDB student Mike East (Kahn lab) for his first author review in Seminars in Cell & Developmental Biology! Models for the functions of Arf GAPs. East MP, Kahn RA. Semin Cell Dev Biol. 2011: 22(1):3-9. doi: 10.1016/j.semcdb.2010.07.002. PMID: 20637885.
