Structural Biology


An important piece of the biological puzzle is understanding the relationship between macromolecular structure and function. In the BCDB program, several faculty members employ physical, chemical, and spectroscopic methods to define molecular structure. This enables the study of protein-DNA, protein-RNA, and protein-protein interactions, as well as defining the behavior of supramolecular complexes at high resolution. Detailed macromolecular structures also facilitate the design of clinically applicable molecules, such as next-generation antibiotics and inhibitors of virus-host interactions.

The following BCDB faculty members conduct research in structural biology: