Our Core Facilities are state-of-the art resources that provide training, equipment, and outsourcing for diverse needs such as functional imaging, gene sequencing and transgenics, microarray analysis, animal behavior, tissue banking, and advanced microscopy. Such resources allow our students to efficiently integrate multiple disciplines to produce innovative findings.
We also have a High Performance Computing Cluster for running complex neural simulations and bioinformatics algorithms.
To date, the program has produced over 150 alumni, and those that have chosen to stay in research have obtained excellent postdoctoral positions to pursue further training, as well as tenure-track faculty appointments. Our alumni compete very well for jobs in academia, industry, and research institutes.
- We study how changes in gene sequence have led to the evolution of alternative phenotypes in a songbird model.
- Channelrhodopsins (green) expressed in the motor thalamus of the monkey after viral transfection
- A cholinergic interneuron (revealed with ChAT, red) expresses channelrhodopsins (green) after viral transfection in the monkey putamen
- Medium spiny neurons in the monkey striatum express channelrhodopsins (revealed with immunoperoxidase) after viral transfection
- Stimulated striatal dopamine release before and after methylphenidate application as measured by fast-scan cyclic voltammetry
- The headphones allow manipulation of the way the birds hear their own songs so that we can study how the brain processes auditory information and learns from experience
- Left: DTI-based white-matter tracts from the genu of the corpus callosum to the PFC in a squirrel monkey. Right: loss of genu-PFC white-matter integrity in aged, cocaine-exposed squirrel monkeys compared to aged controls